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Early studies in the electron microscope by one of us (EP) showed that while images of the fibrin fibres of normal clots looked much like nicely cooked spaghetti, those in a variety of chronic, inflammatory and other conditions looked much as if such spaghetti had been parboiled and stuck together in an unholy mess [90,91,92,93,94,95], a finding referred to at the time as dense matted deposits (see Figure 4)

The 4-month rest period is where the cellular adaptations from each cycle are meant to consolidate

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This allows time for the body to respond to the injection and ensures any minor injection-site reactions have settled before travelling