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Description

GI: Gastrointestinal

The active peptide component, the part that actually activates GLP-1 receptors, makes up a slightly different percentage of the total weight depending on the salt form

The SURPASS trials are designed to evaluate once-weekly tirzepatide doses of 5 mg, 10 mg, and 15 mg with a dose escalation algorithm: starting dose at 2.5 mg weekly for the first 4 weeks, then dose increment of 2.5 mg every 4 weeks until the maintenance dose of 5 mg, 10 mg, or 15 mg is achieved