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found that while almost all veterinary hospitals in their study recommended 12 months of flea and tick prevention, the estimated actual coverage was only 6.1 months based on owner medication purchases from their veterinary hospital over a 12-month period (6)

People choose different amounts depending on their comfort and needs

The reconstitution volume is set by the prescribing provider based on the prescribed dose

The result is a vicious cycle where declining NAD+ leads to worse metabolic function, which can lead to weight gain, which increases NNMT activity further