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This is not a coincidence

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These L cells are found largely in the lower part of the small intestine (the ileum) and the colon

Before we can address this question, some important principles need to be recognized: In interpreting sensations originating from the gut, the threshold at which such sensations arouse concern and become symptomatic is subject to considerable variation and is undoubtedly influenced by many personal, environmental, psychosocial and cultural factors