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Both medications carry similar gastrointestinal side effects (nausea, vomiting, constipation) that typically diminish within weeks as your body adapts

Zonari and her co-founders procured the OS-01 peptide molecule from a peptide library in Brazil, validated it through testing and built One Skin as the consumer-facing brand

These results suggest there is no excess cardiovascular risk with tirzepatide and are consistent with the improvements of numerous surrogate markers of cardiovascular health, including weight reduction, glycemic control with less hypoglycemia, blood pressure reduction, and improvements in the lipid profile