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By boosting your own GH secretion, tesamorelin creates a cascade of effects that bodybuilders care about most: Increased IGF-1 production: GH stimulates the liver to release IGF-1, a critical hormone for muscle protein synthesis, recovery, and hypertrophy

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Nonetheless, gastrointestinal side effects led to treatment discontinuation in 4.5% of participants in semaglutide trials and 6.2% of those receiving the highest dose (15 mg weekly) of tirzepatide

This makes injections more comfortable and easier for daily routines