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The compound was originally studied in preclinical research for its potential gastric protective properties, with early animal model studies examining its effects on stomach lining integrity

Consistent with this observation, the combination of olmesartan and exenatide has been shown to attenuate the renal NADPH oxidase 4 (Nox4) expression in insulin-resistant Otsuka Long-Evans Tokushima Fatty (OLETF) rats (Rodriguez et al., 2020)

First, miR-7 and miR-200A can easily induce the activation of the NRF2 pathway by inhibiting the expression of Keap1 [123, 124]

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