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However, clinical trials of arhalofenate have been conducted to assess its efficacy and safety in the treatment of gout and hyperuricemia

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The latter Cochrane review reported that AOX supplementation in infertile men resulted in a significant increase of CPR (odds ratio (OR) 2.97, 95% confidence interval (CI) 1.91-4.63) although the level of evidence was found to be low (16)