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Food & Drug Administration (FDA) approved the first GLP-1, exenatide, for treatment of type 2 diabetes

A phase II RCT showed superior glycemic control and weight reduction in tirzepatide compared with dulaglutide (another GLP-1 agonist) or placebo, with good tolerability and acceptable safety profiles

These findings are suggestive of a role for increased PPARA in the BWS-hepatocytes contributing to increased fatty acid oxidation, which subsequently coincides with increase in lipid peroxidation, a marker of oxidative stress

If you hold a valid prescription, a medical review officer will contact you to verify it before a result is reported to your employer as positive, meaning a prescription typically protects your employment outcome, though the positive result itself still occurs