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Depletion of GSH with the GSH oxidant diamin disrupted the meiotic spindle apparatus ( 2 O 2 concentrations during in vitro maturation displayed concentration dependent increased incidences of misaligned chromosomes, spindle abnormalities, and aneuploidy ( A number of studies have shown the ability of antioxidant treatments to protect mouse oocytes from chromosome and spindle misalignments and aneuploidy

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Activating the output gate to adjust the cells state determines the hidden state at the current time step