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On a more experimental level, an IgG Fc variant engineered for improved binding to both FcRn and activating FcRs by introducing six amino acid substitutions (Y296W/K334N/P352S/A378V/V397M/N434Y) has been shown to be as efficacious as IVIg in mouse models of arthritis and ITP [403]

10 Slowing of gastric emptying, primarily within the first hour post meal, has been demonstrated with short-term liraglutide treatment at doses up to 1.8 mg in T2DM, 11, 12 although no dose response between liraglutide 1.2 and 1.8 mg was observed

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Type 2 diabetes and glycemic control: Research explores its effects on fasting glucose, HbA1c, and postprandial glycemia via slowed gastric emptying, reduced food intake, and possible direct pancreatic/islet effects