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A once-daily commitment to weight loss with the Wegovy pill Once-daily Wegovy pill dose-escalation schedule 1 Start your patients at the 1.5 mg dose, escalating the dose every 30 days until the 25 mg maintenance dose is reached

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Where the Science Is Headed Now The next phase of the GLP-1 story is less about format and more about stability in the body over time, a shift that became tangible in December 2025 when the FDA approved Novo Nordisks oral semaglutide (Wegovy), the first daily GLP-1 pill cleared for obesity treatment