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GHK-Cu has a lower effective concentration range than the other components, typically requiring higher mass to achieve equivalent receptor engagement in tissue models

Quando empregado corretamente, em concentraes adequadas e em veculos compatveis, apresenta excelente perfil de segurana, sendo indicado inclusive para peles sensibilizadas e para uso ps-procedimento Na prtica clnica, o GHK-Cu amplamente utilizado em sruns regeneradores e protocolos de reparao drmica

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Step 3: Preparation of compound of formula-12 Acetonitrile (150 ml) was added to compound obtained in step 2 at 25-30C and stirred for 10 min