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Key Tirzepatide Formulations Mounjaro: FDA-approved for type 2 diabetes management Zepbound: FDA-approved for chronic weight management in adults with BMI 30 or greater, or BMI 27 or greater with a weight-related comorbidity Efficacy Comparison The SURMOUNT-1 trial showed tirzepatide at 15 mg weekly produced average weight loss of 22.5% of body weight at 72 weeks, compared to approximately 15% to 17% with semaglutide 2.4 mg in the STEP trials

For instance, you might experience increased gastrointestinal distress, such as diarrhea or constipation, or other systemic reactions that could complicate your health status

Radiology 21 , 49 (2015)

In clinical research settings, commonly reported effects include: Nausea Delayed gastric emptying Gastrointestinal discomfort Reduced appetite Side effect profiles vary depending on receptor selectivity and dose titration in controlled studies