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On admission, 5% of the 41 patients in a designated hospital in Wuhan experienced thrombocytopenia

Interventions aimed at blocking collagen and hyaluronan production, such as a neutralizing antibody against TGF- [127], the angiotensin inhibitor losartan [128,129,130,131], or the antifibrotic drugs tranilast and pirfenidone [132,133,134] have shown promising results in alleviating solid stress and increasing breast tumor blood supply and drug delivery

The supplementation of exogenous DNase I effectively reduces the deposition of renal immune complexes and inhibits the NFB pathway as well as the release of inflammatory cytokines [361]

Based on mounting evidence, GLP-1 receptor agonists and their multi-target derivatives undoubtedly represent a paradigm shift in NASH management