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Description

The incidence peaks in the fourth to fifth decades

PMC 5463186

Future directions Future research should explore combination strategies, including dual and triple therapy regimens pairing tirzepatide with other agents including sodium-glucose cotransporter-2 inhibitors and the non-steroidal mineralocorticoid receptor antagonist, finerenone, which have been shown to offer additive cardiorenal protection alongside GLP-1RAs [35]