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Clinical trials should include diverse patient populations, encompassing different lupus phenotypes, disease severities, and demographic characteristics, to ensure generalizability of findings and facilitate personalized treatment approaches

PM can be composed of metals, carbon, sulfates, nitrates, polycyclic aromatic hydrocarbons (PAHs), biological compounds, and can also form secondary PM through the nucleation and coagulation of gaseous pollutants onto primary PM [4]

McEwen, Natalie Rasgon

conducted a study pre-treating human subjects with an intranasally delivered cocktail of antioxidant oils (soy oil, coconut oil, orange oil, aloe vera oil, peppermint oil, and vitamin E oil) followed by acute ozone exposure [87]