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The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity

ME: methodology, writing (original draft), and formal analysis

Besides, the elevated ratio of free to conjugated BA (CA/GCA + TCA) denoted the enhanced activity of bile salt hydrolase (BSH) (Juarez-Fernandez et al., 2021), which promoted the deconjugation of conjugated BA and conversion to free BA