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Indication: As an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of: 30 kg/m 2 or greater (obesity), or 27 kg/m 2 or greater (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, dyslipidemia, or obstructive sleep apnea

If brain fog persists beyond two weeks and affects work or safety, first ask for blood glucose control measures, vitamin B12, ferritin, and thyroid function tests, as these results guide immediate treatment

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An improved time- and labor-efficient protocol for mouse primary hepatocyte isolation