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GLP-1-based therapies, such as GLP-1 receptor agonists, glucose-dependent insulinotropic polypeptide (GIP) receptor agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors, improve glucose control through various mechanisms including increased insulin secretion, slower gastric emptying, and reduced postprandial glucagon and food intake

Should I discuss my Crohn's disease with my doctor before starting GLP-1 therapy

Clinical studies should note the long-term (i.e., beyond 68 weeks) safety and effectiveness of semaglutide as it still needs to be fully understood