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Wellbutrin SR Administration: Take twice daily, approximately 8 hours apart The typical dosing schedule is a morning dose and an early evening dose Avoid taking the second dose too close to bedtime to prevent insomnia Starting dose: 150mg once daily for 3 days, then 150mg twice daily Dose increases should occur gradually, with at least 3 days between changes Maximum: 200mg twice daily (400mg total daily dose) Wellbutrin XL Administration: Take once daily in the morning, around the same time each day Starting dose: 150mg once daily for at least 4 days May increase to 300mg once daily based on response and tolerance Maximum: 450mg once daily for depression, 300mg for seasonal affective disorder prevention Both SR and XL tablets must be swallowed whole without cutting, crushing, or chewing

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