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Warning signs of excessive muscle breakdown include feeling weaker than usual, having trouble with daily activities like climbing stairs or carrying groceries, getting tired more easily, or noticing your clothes fit differently around your arms and legs

Follow the dose-escalation schedule to reduce the risk of gastrointestinal adverse reactions 1 If patients do not tolerate a dose during dose escalation, consider delaying dose escalation 1 The safety and effectiveness of Wegovy tablets have not been established in pediatric patients

Blundell J, Finlayson G, Axelsen M, Flint A, Gibbons C, Kvist T, et al

Food and Drug Administration (FDA) issued a declaratory order determining that the shortage of diabetes and weight-loss tirzepatide injection products (Mounjaro and Zepbound