The used methods included high-performance liquid chromatography coupled with mass spectrometry, Alamar Blue assay, real-time qPCR, and the Mito Stress Test of the Seahorse Analyzer (Agilent, Santa Clara, California, USA)
Provides Antioxidant & Anti-Inflammatory Protection As a powerful antioxidant , GHK-Cu protects skin cells from environmental damage, pollution, and UV exposure
The function of GPX4 is precisely regulated by nuclear factor E2-related factor 2 (NRF2), a key transcription factor that activates the expression of various antioxidant genes, including those encoding GSH synthetase and superoxide dismutase (SOD), facilitating the clearance of excess ROS (Xie et al., 2016
Frry N, Santonen T, Porras SP, Fucic A, Leso V, Bousoumah R, Duca RC, El Yamani M, Kolossa-Gehring M, Ndaw S