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Similarly, in GPx1 / mice, deficiency of GPx1 increased ROS (as measured by DCF fluorescence of brain homogenates), lipid peroxidation, and protein carbonylation in brains exposed to the A peptide, whereas forced overexpression of GPx1 in the GPx1 / mice attenuated these detrimental effects [124]

It is referred to as "the mother of all antioxidants" because it recycles the antioxidants vitamins C and E

Given these anti-inflammatory effects, there is speculation that GLP-1 medicines could impair host immune defenses

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