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Bringing this back to homocysteine, it is known that when homocysteine is elevated in the blood, its precursor, S-adenosylhomocysteine, is elevated intracellularly

(11) T J Smith (2010) Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases

Laboratory studies have shown that it has no effect on ACTH, prolactin, follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone or cortisol