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These volumetric deficits correlate with functional impairments: positron emission tomography (PET) scans reveal hypometabolism in the dorsolateral PFC and hyperactivation of the amygdala during negative emotional stimuli, mirroring neural signatures observed in non-alcoholic MDD patients (Amico et al

10.1515/9783110527872-009 16 De FranceschiL.BertoldiM.MatteA.Santos FrancoS.PantaleoA.FerruE.et al (2013)

The vial should remain at atmospheric pressure throughout its lifespanif liquid sprays back when you remove the needle, the vial is contaminated and should be discarded

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