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The new indication is to reduce the risk of major adverse cardiovascular events (MACE) such as heart attack, stroke or death in adults with type 2 diabetes and known heart disease.[1] Additional details were added to the Rybelsus (semaglutide) tablets 7 mg or 14 mg prescribing information about the primary analysis for PIONEER 6 trial

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[33] Men with new-onset ED should undergo cardiovascular risk assessment, including blood pressure, lipid profile, and consideration of stress testing when appropriate