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Physical activity recommendations in patients with obesity on GLP-1RAs Patients receiving GLP-1RAs experience significant weight loss but are also at increased risk of lean body mass and bone density loss

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Reported side effects are minimal, but some users in experimental settings have described: Mild fatigue Temporary nausea Headache or dizziness Long-Term Risks The long-term impact of MOTS-c therapy remains unknown, raising concerns about possible risks from prolonged use: Metabolic Overstimulation: chronic AMPK activation may interfere with natural energy signaling