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In this fashion, we hope to provide data that will support our conclusion that the intestinal paracellular space is a major route of transport of water and small solutes such as ions and small soluble organic molecules between the lumen and submucosal space, and not a means by which large molecules, lipophilic substances, or macromolecular structures such as proteins, particulate matter, or intact bacteria are absorbed

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As we age, the volume of glutathione maintained in the body reduces dramatically, and can benefit from supplementation

2.4 In vitro cell culture Caco-2 cells (passage #51) were cultured in DMEM (supplemented with 10% FBS) for 3 days on plastic coverslips at the bottom of 1 mL wells in 24-well cluster plates at a density of 1 10 6 cells/mL